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Clinical research towards novel diagnostic and therapeutic strategies

Aiming at the integration of research activities across the broad field of research including infectious, parasitological and genetic diseases of animals and Man.

 

AIMS/TARGETS

The aim is to develop clinically safe and less costly diagnostic tools and therapies for naturally occurring problems in animal medicine. In addition this thematic line aims to develop novel animal models of human disease and to foster translational research in veterinary medicine . Difficult challenges like the development of novel cancer therapies and the effective treatment and control of chronic bacterial infections will also be addressed. Another major area where the development of novel therapeutic approaches is a priority is human and animal reproduction.

 

TASKS

Research in this thematic line will be essentially carried out in 8 laboratories: Clinical Research, Microbiology and Immunology, Infectious Disease and Epidemiology, Parasitology Reproduction and Development, Antibiotic Resistance , Pathology and Animal Behaviour and Welfare. The most important tasks to achieve the proposed targets are:

Clinical Research Laboratory tasks: collect clinical material for medical research and implement clinical trials, with emphasis given to the fields of Ophtalmology and Dermatology.

Microbiology and Immunology Laboratory tasks: study patterns of bacterial, viral and diseases affecting both animals and humans, and develop novel therapeutic and control strategies for a sustainable health, including vaccines, phage therapy and antimicrobial peptides.

Infectious disease and Epidemiology Laboratory tasks : microbial surveillance in shared ecosystems, develop new diagnostic tools based on biosensors and characterise virulence mechanisms of emerging zoonotic pathogens affecting health quality on the wider concept of "One Health".

Reproduction and Development Laboratory tasks : study reproductive and developmental events and disturbances such as cancer, involving genetic manipulation and analysis, cell and tissue culture and imaging, and evaluation of hormonal, biochemical and clinical parameters.

Antibiotic Resistance Laboratory tasks : test for antibiotic resistance bacterial isolates obtained from clinical samples and food products of animal origin.

Pathology Laboratory tasks : collaborate in various projects requiring histopathological analysis and pursue own projects concerned with naturally occurring tumours in animals.

Animal Behaviour/Welfare Laboratory tasks : assess problems such as aggressiveness, reaction to pain, animal/owners relationship, and develop and implement evaluation systems to determine levels of wellbeing/stress in production animals.