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Reproduction and Development

Publications since 2009

Publications of the "Reproduction and Development Lab" team members

 

2021


Amaral, A., Fernandes, C., Rebordão, M.R., Szóstek-Mioduchowska, A., Lukasik, K., Pinto-Bravo, P., Telo da Gama, L., Jan Skarzynski, D., Ferreira-Dias, G., 2021. Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions. Animals, 11, 208. 

Batista, M. R., Diniz, P., Murta, D., Torres, A., Lopes-da-Costa, L., & Silva, E., 2021. Balanced Notch-Wnt signaling interplay is required for mouse embryo and fetal development, Reproduction, 161(4), 385-398. 

Martinez, C.A., Cambra, J.M., Lucas, X., Ferreira-Dias, G., Rodriguez-Martinez, H., Gil, M.A., Martinez, E.A., Cuello, C., Parrilla, I., 2021. Intrauterine Infusion of TGF-β1 Prior to Insemination, Alike Seminal Plasma, Influences Endometrial Cytokine Responses but Does Not Impact the Timing of the Progression of Pre-Implantation Pig Embryo Development. Biology, 10, 159. 

Pinto-Bravo, P., Rebordão, M.R., Amaral, A., Fernandes, C., Galvão, A., Silva, E., Pessa-Santos, P., Alexandre-Pires, G., Roberto da Costa, R.P., Skarzynski, D.J., Ferreira-Dias, G., 2021. Microvascularization and Expression of Fibroblast Growth Factor and Vascular Endothelial Growth Factor and Their Receptors in the Mare Oviduct. Animals, 11, 1099. 

Silva, M.F., Pereira, A.L., Fraqueza, M.J., Pereira, G., Mateus, L., Lopes-da-Costa, L., Silva, E., 2021 Genomic and Phenotypic Characterization of Campylobacter fetus subsp. venerealis Strains. Microorganisms, 9, 340. 

 

2020


Amaral, A., Fernandes, C., Morazzo, S., Rebordão, M.R., Szóstek-Mioduchowska, A., Lukasik, K., Gawronska-Kozak, B., Telo da Gama, L., Skarzynski, D.J. and Ferreira-Dias, G., 2020. The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare. Front. Vet. Sci. 7:582211.

Amaral, A., Fernandes, C., Rebordão, M.R., Szóstek-Mioduchowska, A., Lukasik, K., Gawronska-Kozak, B., Telo da Gama, L., Skarzynski, D.J., Ferreira-Dias, G., 2020. The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium. Animals, 10, 863. 

Barranco, I., Padilla, L., Martinez, C.A., Alvarez-Rodriguez, M., Parrilla, I., Lucas, X., Ferreira-Dias, G., Yeste, M., Rodriguez-Martinez, H., Roca, J., 2020. Seminal Plasma Modulates miRNA Expression by Sow Genital Tract Lining Explants. Biomolecules, 10, 933. 

Batista, M.R., Diniz, P., Torres, A., Murta, D., Lopes-da-Costa, L., Silva, E., 2020. Notch signaling in mouse blastocyst development and hatching. BMC Dev Biol 20, 9. 

De Zoysa, P., Liu, J., Toubat, O., Choi, J., Moon, A., Gill, P.S., Duarte, A., Sucov, H.M., Kumar, S.R., 2020. Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression. Development; 147 (17): dev185249.

Domino, M., Jasinskim T,, Kautz, E,, Juszczuk-Kubiak, E., Ferreira-Dias, G., Zabielski, R., Sady, M., Gajewski, Z., 2020. Expression of genes involved in the NF-κB-dependent pathway of the fibrosis in the mare endometrium. Theriogenology;147:18-24. 

Miró, J., Gutiérrez-Reinoso, M., Silva, J.Ad., Fernandes, C., Rebordão, M.R., Alexandre-Pires, G., Catalán, J. and Ferreira-Dias, G., 2020. Collagen and Eosinophils in Jenny's Endometrium: Do They Differ With Endometrial Classification? Front. Vet. Sci. 7:631.

Parrilla, I., Martinez, C.A., Cambra, J.M., Lucas, X., Ferreira-Dias, G., Rodriguez-Martinez, H., Cuello, C., Gil, M.A., Martinez, E.A., 2020. Blastocyst-Bearing Sows Display a Dominant Anti-Inflammatory Cytokine Profile Compared to Cyclic Sows at Day 6 of the Cycle. Animals, 10, 2028. 

Pereira, G., Bexiga, R., Chagas e Silva, J., Silva, E., Ramé, C., Dupont, J., Guo, Y., Humblot, P., & Lopes-da-Costa, L., 2020. Adipokines as biomarkers of postpartum subclinical endometritis in dairy cows, Reproduction, 160(3), 417-430. 

Podico, G., Canisso, I.F., Roady, P.J., Austin, S.M., Carossino, M., Balasuriya, U., Ellerbrock, R.E., Lima, F.S., Ferreira-Dias, G., Douglas, R.H., 2020. Uterine responses and equine chorionic gonadotropin concentrations after two intrauterine infusions with kerosene post early fetal loss in mares. Theriogenology;147:202-210.

Silva, M.F., Pereira, G., Carneiro, C., Hemphill, A., Mateus, L., Lopes-da-Costa, L., Silva, E., 2020. Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls. PLoS ONE 15(1): e0227500. 

Silva, M.F., Duarte, A., Pereira, G. Mateus, L., Lopes-da-Costa, L., Silva, E., 2020. Assessment of Campylobacter fetus subsp. venerealis molecular diagnosis using clinical samples of bulls. BMC Vet Res 16, 410. 

Skarzynski, D.J., Szóstek-Mioduchowska, A.Z., Rebordão, M.R., Jalali, B.M., Piotrowska-Tomala, K.K., Leciejewska, N., Łazarczyk, M., Ferreira-Dias, G.M., 2020. Neutrophils, monocytes and other immune components in the equine endometrium: Friends or foes? Theriogenology;150:150-157. 

Szóstek-Mioduchowska, A., Leciejewska, N., Zelmańska, B., Staszkiewicz-Chodor, J., Ferreira-Dias, G., Skarzynski, D., 2020. Lysophosphatidic acid as a regulator of endometrial connective tissue growth factor and prostaglandin secretion during estrous cycle and endometrosis in the mare. BMC Vet Res 16, 343. 

Szóstek-Mioduchowska, A.Z., Baclawska, A., Rebordão, M.R., Ferreira-Dias, G., Skarzynski, D.J., 2020. Prostaglandins effect on matrix metallopeptidases and collagen in mare endometrial fibroblasts. Theriogenology. Sep 1;153:74-84. 

Trindade, A.; Duarte, A., 2020. Notch Signaling Function in the Angiocrine Regulation of Tumor Development. Cells, 9, 2467. 

 

2019


Fonseca, E., Mesquita, P., Marques, C.C., Baptista, M.C., Pimenta, J., Matos, J.E., Soveral, G., Pereira, R.M.L.N., 2020. Modulation of P2Y2 receptors in bovine cumulus oocyte complexes: effects on intracellular calcium, zona hardening and developmental competence. Purinergic Signal;16(1):85-96.

Fradinho, M.J., Mateus, L., Bernardes, N., Bessa, R.J.B., Caldeira, R.M., Ferreira-Dias, G., 2019. Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse: A longitudinal study. PLoS One;14(7):e0219900. 

Martinez, C.A., Cambra, J.M., Parrilla, I., Roca, J., Ferreira-Dias, G., Pallares, F.J., Lucas, X., Vazquez, J.M., Martinez, E.A., Gil, M.A., Rodriguez-Martinez, H., Cuello, C., Álvarez-Rodriguez, M., 2019. Seminal Plasma Modifies the Transcriptional Pattern of the Endometrium and Advances Embryo Development in Pigs. Front Vet Sci;6:465. 

Alpoim-Moreira, J., Fernandes, C., Rebordao, M.R., Amaral, A., Pinto-Bravo, P., Bliebernicht, M., Skarzynski, D.J., Ferreira-Dias, G., 2019. Collagens and DNA methyltransferases in mare endometrosis. Reproduction in Domestic Animals 54, 46-52. 

Mendonca, L., Trindade, A., Carvalho, C., Correia, J., Badenes, M., Gigante, J., Duarte, A., 2019. Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and circulating tumor cells. Clinical & Experimental Metastasis 36, 365-380. 

Rebordao, M.R., Amaral, A., Lukasik, K., Szostek-Mioduchowska, A., Pinto-Bravo, P., Galvao, A., Skarzynski, D.J., Ferreira-Dias, G., 2019. Impairment of the antifibrotic prostaglandin E-2 pathway may influence neutrophil extracellular traps-induced fibrosis in the mare endometrium. Domestic Animal Endocrinology 67, 1-10.

Walewska, E., Wolodko, K., Skarzynski, D., Ferreira-Dias, G., Galvao, A., 2019. The Interaction Between Nodal, Hypoxia-Inducible Factor 1 Alpha, and Thrombospondin 1 Promotes Luteolysis in Equine Corpus Luteum. Frontiers in Endocrinology 10.

 

2018


Amaral, A., Fernandes, C., Lukasik, K., Szostek-Mioduchowska, A., Baclawska, A., Rebordao, M.R., Aguiar-Silva, J., Pinto-Bravo, P., Skarzynski, D.J., Ferreira-Dias, G., 2018. Elastase inhibition affects collagen transcription and prostaglandin secretion in mare endometrium during the estrous cycle. Reproduction in Domestic Animals 53, 66-69.

Fradinho, M.J., Mateus, L., Bessa, R.J.B., Caldeira, R.M., Ferreira-Dias, G., 2018. Age-related changes of bone ultrasound measurements and metabolic indicators in the young horse. Livest Sci 211, 104-110.

Galvao, A., Wolodko, K., Rebordao, M.R., Skarzynski, D., Ferreira-Dias, G., 2018. TGFB1 modulates in vitro secretory activity and viability of equine luteal cells. Cytokine 110, 316-327.

Galvao, A.M., Skarzynski, D., Ferreira-Dias, G., 2018. Luteolysis and the Auto-, Paracrine Role of Cytokines From Tumor Necrosis Factor a and Transforming Growth Factor beta Superfamilies, Vitam. Horm. 107,287-315.

Marques, C.C., Santos-Silva, C., Rodrigues, C., Matos, J.E., Moura, T., Baptista, M.C., Horta, A.E.M., Bessa, R.J.B., Alves, S.P., Soveral, G., Pereira, R., 2018. Bovine oocyte membrane permeability and cryosurvival: Effects of different cryoprotectants and calcium in the vitrification media. Cryobiology 81, 4-11.

Miranda, S., Carolino, N., Vilhena, H., Payan-Carreira, R., Pereira, R.M.L.N., 2018. Early embryo development, number, quality, and location and the relationship with plasma progesterone in dogs. Animal Reproduction Science 198, 238-245. 

Pedrosa, A. R., Trindade, A., Duarte, A., 2018. Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer. Methods Mol. Biol. 1786, 29-54.

Pereira, R.M., Mesquita, P., Pires, V.M.R., Baptista, M.C., Barbas, J.P., Pimenta, J., Horta, A.E.M., Prates, J.A.M., Marques, C.C., 2018. Prion protein testis specific (PRNT) gene polymorphisms and transcript level in ovine spermatozoa: Implications in freezability, fertilization and embryo production. Theriogenology 115, 124-132.

Pinto-Bravo, P., Rebordao, M.R., Amoral, A., Fernandes, C., Cuello, C., Parrilla, I., Martínez, E., Da Costa, R.P.R., Skarzynski, D.J., Ferreira-Dias, G., 2018. Is mare endometrosis linked to oviduct fibrosis? Pferdeheilkunde 34, 43-46.

Rebordao, M.R., Amaral, A., Lukasik, K., Szostek-Mioduchowska, A., Pinto-Bravo, P., Galvao, A., Skarzynski, D.J., Ferreira-Dias, G., 2018. Constituents of neutrophil extracellular traps induce in vitro collagen formation in mare endometrium. Theriogenology 113, 8-18.

 

2017


Alexandre-Pires, G., Martins, C., Galvao, A.M., Miranda, M., Silva, O., Ligeiro, D., Nunes, T., Ferreira-Dias, G., 2017. Understanding the Inguinal Sinus in Sheep (Ovis aries)-Morphology, Secretion, and Expression of Progesterone, Estrogens, and Prolactin Receptors. Int. J. Mol. Sci. 18.

Badenes, M., Trindade, A., Pissarra, H., Lopes-da-Costa, L., Duarte, A., 2017. Delta-like 4/Notch signaling promotes ApcMin/+ tumor initiation through angiogenic and non-angiogenic related mechanisms. BMC Cancer 17, 50.

Felix, N.M., Leal, R.O., Goy-Thollot, I., Walton, R.S., Gil, S.A., Mateus, L.M., Matos, A.S., Niza, M.M.R.E., 2017. Effects of buprenorphine in the adrenal, thyroid, and cytokine intra-operative responses in a rat model (Rattus norvegicus): a preliminary study. Iranian Journal of Basic Medical Sciences 20, 368-379.

Pereira-Figueiredo, I., Castellano, O., Riolobos, A.S., Ferreira-Dias, G., Lopez, D.E., Sancho, C., 2017. Long-Term Sertraline Intake Reverses the Behavioral Changes Induced by Prenatal Stress in Rats in a Sex-Dependent Way. Frontiers in Behavioral Neuroscience 11, 99.

Pinto-Bravo, P., Galvao, A., Rebordao, M.R., Amaral, A., Ramilo, D., Silva, E., Szostek-Mioduchowska, A., Alexandre-Pires, G., da Costa, R.R., Skarzynski, D.J., Ferreira-Dias, G., 2017. Ovarian steroids, oxytocin, and tumor necrosis factor modulate equine oviduct function. Domest. Anim. Endocrin. 61, 84-99.

Rebordao, M.R., Alexandre-Pires, G., Carreira, M., Adriano, L., Carneiro, C., Nunes, T., Mateus, L., Ferreira-Dias, G., 2017. Bacteria causing pyometra in bitch and queen induce neutrophil extracellular traps. Vet. Immunol. Immunop. 192, 8-12.

Rebordao, M.R., Galvao, A., Pinto-Bravo, P., Pinheiro, J., Gamboa, S., Silva, E., Mateus, L., Ferreira-Dias, G., 2017. Endometrial prostaglandin synthases, ovarian steroids, and oxytocin receptors in mares with oxytocin-induced luteal maintenance. Theriogenology 87, 193-204.

Rodrigues, P.M., Afonso, M.B., Simao, A.L., Carvalho, C.C., Trindade, A., Duarte, A., Borralho, P.M., Machado, M.V., Cortez-Pinto, H., Rodrigues, C.M.P., Castro, R.E., 2017. miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice. Cell Death & Disease 8, e2748.

Trindade, A., Djokovic, D., Gigante, J., Mendonca, L., Duarte, A., 2017. Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo. BMC Cancer 17, 189.

 

2016


Pedrosa, A.R., Graca, J.L., Carvalho, S., Peleteiro, M.C., Duarte, A., Trindade, A. 2016. Notch signaling dynamics in the adult healthy prostate and in prostatic tumor development. Prostate 76:80-96. 

Mesquita, P., Garcia, V., Marques, M.R., Santos-Silva, F., Oliveira Sousa. M.C., Carolino, I., Pimenta, J., Fontes, C.M., Horta, A.E., Prates, J.A., Pereira R.M. 2016. The prion-related protein (testis-specific) gene (PRNT) is highly polymorphic in Portuguese sheep. Anim Genet. 47:128-132.

Felix, N.M., Goy-Thollot, I., Walton, R.S., Gil, S.A., Mateus, L.M., Matos, A.S., Niza, M., 2016. Effects of etomidate in the adrenal and cytokine responses to hemorrhagic shock in rats. European Journal of Inflammation 14, 147-161.

Galvao, A., Skarzynski, D., Ferreira-Dias, G., 2016. Nodal Promotes Functional Luteolysis via Down-Regulation of Progesterone and Prostaglandins E2 and Promotion of PGF2 alpha Synthetic Pathways in Mare Corpus Luteum. Endocrinology 157, 858-871.

Henriques, S., Silva, E., Cruz, S., Silva, M.F., Ferreira-Dias, G., Lopes-da-Costa, L., Mateus, L., 2016. Oestrous cycle-dependent expression of Fas and Bcl2 family gene products in normal canine endometrium. Reprod. Fert. Develop. 28, 1307-1317.

Henriques, S., Silva, E., Silva, M.F., Carvalho, S., Diniz, P., Lopes-da-Costa, L., Mateus, L., 2016. Immunomodulation in the canine endometrium by uteropathogenic Escherichia coli. Vet. Res. 47.

Murta, D., Batista, M., Silva, E., Trindade, A., Henrique, D., Duarte, A., Lopes-da-Costa, L., 2016. Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes. Andrology 4, 314-327.

Murta, D., Batista, M., Trindade, A., Silva, E., Mateus, L., Duarte, A., Lopes-da-Costa, L., 2016. Dynamics of Notch signalling in the mouse oviduct and uterus during the oestrous cycle. Reprod. Fert. Develop. 28, 1663-1678.

 Rebordao, M.R., Amaral, A., Galvao, A., Szotek, A.Z., Pinto-Bravo, P., Dariusz, S.S., Ferreira-Dias, G., 2016. Dual effect of hormones on mare reproductive physiology and dysfunction. Pferdeheilkunde 32, 36-38. 

 

2015


Djokovic, D., Trindade, A., Gigante, J., Pinho, M., Harris, A.L., Duarte, A., 2015. Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas. BMC Cancer 15:608.

Murta, D., Batista, M., Silva E., Trindade, A., Mateus, L., Duarte, A., Lopes-da-Costa, L. 2015. Differential expression of Notch component and effector genes during ovarian follicle and corpus luteum development along the estrous cycle. Reprod. Fertil. Dev. 27:1038-1048. 

Pedrosa, A.R., Trindade, A., Carvalho, C., Graca, J., Carvalho, S., Peleteiro, M.C., Adams, R.H., Duarte, A., 2015. Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions. Oncotarget 6:24404-24423.

Pedrosa, A.R., Trindade, A., Fernandes, A.C., Carvalho, C., Gigante, J., Tavares, A.T., Dieguez-Hurtado, R., Yagita, H., Adams, R.H., Duarte, A., 2015. Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1. Arterioscler Thromb Vasc Biol. 35: 1134-1146. 

Romao, R., Marques, C.C., Baptista, M.C., Barbas, J.P., Horta, A.E.M., Carolino, N., Bettencourt, E., Pereira, R.M., 2015. Cryopreservation of in vitro-produced sheep embryos: Effects of different protocols of lipid reduction. Theriogenology 84: 118-126. 

Torres, A., Batista, M., Diniz, P., Silva, E., Mateus, L., Lopes-da-Costa, L. 2015. Effects of oocyte donor age and embryonic stage of development on transcription of genes coding for enzymes of the prostaglandins and progesterone synthesis pathways in bovine in vitro produced embryos. Zygote 23:802-812.

Matos, J.E., Marques, C.C., Moura, T.F., Baptista, M.C., Horta, A.E.M., Soveral, G., Pereira, R.M.L.N., 2015. Conjugated linoleic acid improves oocyte cryosurvival through modulation of the cryoprotectants influx rate. Reprod. Biol. Endocrinol. 13:60

Fradinho, M.J., Vale, A.C., Bernardes, N., Caldeira, R.M., Vaz, M.F., Ferreira-Dias, G., 2015. Biomechanical properties of the equine third metacarpal bone: In vivo quantitative ultrasonography versus ex vivo compression and bending techniques. J. Equine Vet. Sci. 35:198-205. 

Jahnsen, E.D., Trindade, A., Zaun, H.C., Lehoux, S., Duarte, A., Jones, E.A.V., 2015. Notch1 is pan-endothelial at the onset of flow and regulated by flow. PLoS ONE 10:e0122622.
 

2014


Rebordão, M.R., Galvão, A., Szóstek, A., Amaral, A., Mateus, L., Skarzynski, D.J., Ferreira-Dias, G. 2014. Physiopathologic mechanisms involved in mare endometrosis. Reprod. Dom. Anim. 49 suppl.4:82-87.

Payan-Carreira, R., Santos, C., Miranda, S., Pereira, R.M.L.N., Santos, D., Pires, M.A. 2014. Temporal changes in neutral endopeptidase/CD10 immunoexpression in the cyclic and early pregnant endometrium. Theriogenology 82:815-826.

Rebordão, M.R., Carneiro, C., Alexandre-Pires, G., Brito, P., Pereira, C., Nunes, T., Galvão, A., Leitão, A., Vilela, C., Ferreira-Dias, G. 2014. Neutrophil Extracellular Traps Formation by Bacteria Causing Endometritis in the Mare. J. Reprod. Immunol. 106:41-19.

Boruszewska, D., Torres, A.C., Kowalczyk-Zieba, I., Diniz, P., Batista, M., Lopes-da-Costa, L., Woclawek-Potocka, I. 2014. The effect of lysophosphatidic acid during in vitro maturation of bovine oocytes: embryonic development and mRNA abundances of genes involved in apoptosis and oocyte competence. Mediators Inflamm. 2014: 670670.

Fradinho, M.J., Correia, M.J., Grácio, V., Bliebernicht, M., Farrim, A., Mateus, L., Martin-Rosset, W., Bessa, R.J.B., Caldeira, R.M., Ferreira-Dias, G. 2014. Effects of body condition and leptin on the reproductive performance of Lusitano mares on extensive systems. Theriogenology 81:1214-1222.

Galvão, A., Tramontano, A., Rebordão, M.R., Amaral, A., Bravo, P.P., Szóstek, A., Skarzynski, D., Mollo, A., Ferreira-Dias, G. 2014. Opposing roles of leptin and Ghrelin in Equine Corpus luteum Regulation: An in vitro study. Mediators Inflamm. 2014:682193.

Henriques, S., Silva, E., Lemsaddek, A., Lopes-da-Costa, L., Mateus, L. 2014. Genotypic and phenotypic comparison of Escherichia coli from uterine infections with different outcomes: clinical metritis in the cow and pyometra in the bitch. Vet. Microbiol. 170:109-116.

Murta, D., Batista, M., Silva, E., Trindade, A., Henrique, D., Duarte, A., Lopes-da-Costa, L. 2013. Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle. PLoS ONE 8:e72767.

Prates, E.G., Nunes, J.T., Pereira, R.M.L.N. 2014. A role of lipid metabolism during cumulus-oocyte complex maturation: impact of lipid modulators to improve embryo production. Mediators Inflamm. 2014:ID 692067.

Rebordão, M.R., Pereira, C., Galvão, A., Bravo, P.P., Szóstek, A., Skarzynski, D.J., Ferreira-Dias, G. 2014. What is new on the physiopathology of endometrosis in the mare? Pferdeheilkunde 30:15-18

Szóstek A.Z., Galvão, A.M., Piotrowska-Tomala, K.K., Ferreira-Dias, G.M., Skarzynski, D.J. 2014. Ovarian steroids affect prostaglandin production in equine endometrial cells in vitro. J. Endocrinol. 220:263–276.

Szóstek, A.Z., Adamowski, M., Galvão, A.M., Ferreira-Dias, G.M., Skarzynski, D.J. 2014. Ovarian steroid-dependent Tumor necrosis factor-α production and its action on the equine endometrium in vitro. Cytokine 67:85-91.

Torres, A.C., Boruszewska, D., Batista, M., Kowalczyk-Zieba, I., Diniz , P., Sinderewicz, E., Saulnier-Blache, J.S., Woclawek-Potocka, I., Lopes-da-Costa, L. 2014. Lysophosphatidic acid signaling in late cleavage and blastocyst stage bovine embryos. Mediators Inflamm. 2014:678968.

Alexandre-Pires G., Martins C., Galvão, A.M., Correia, M., Ramilo, D., Ligeiro, D., Nunes, T., Caldeira, R., Ferreira-Dias, G. 2014. Morphological aspects and expression of estrogen and progesterone receptors in the interdigital sinus in cyclic ewesMicrosc. Res. Techn. 77:313-325.

 

2013


Barbas, J.P., Horta, A.E.M., Marques, C.C., Baptista, M.C., Mascarenhas, R.D., Martins, D.O., Vasques, M.I., Pereira, R.M., Cavaco-Gonçalves, S. 2013. The fertility increase after misoprostol administration is differently expressed when sheep are inseminated with chilled or frozen-thawed semen. Small Rum. Res. 113:398-401.

Cristofaro, B., Shi, Y., Faria, M., Suchting, S., Leroyer, A.S., Lopes-da-Costa, L., Duarte, A., Zovein, A.C., Iruela-Arispe, M.L., Nhi, L.R., Kubis, N., Henrion, D., Loufrani, L., Todiras, M., Schleifenbaum, J., Gollash, M., Zhuang, Z.W., Simons, M., Eichmann, A., lle Noble F. 2013. Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development 140:1720-1729.

Ferreira-Dias, G., Botelho, M., Zagrajczuk, A., Rebordão, M.R., Galvão, A.M., Pinto Bravo, P., Piotrowska-Tomala, K., Szóstek, A.Z., Wiczkowski, W., Piskula, M., Fradinho, M.J., Skarzynski, D.J. 2013. Coumestrol and its metabolite in mares’ plasma after ingestion of phytoestrogen rich plants: potent endocrine disruptors inducing infertility. Theriogenology 80:684-692.

Fradinho, M.J., Correia, M.J., Beja, F., Rosa, A., Perestrello, F., Bessa, R.J.B., Ferreira-Dias, G., Caldeira, R.M. 2013. Nutritional status of Lusitano broodmares on extensive feeding systems: body condition, live weight and metabolic indicators. It. J. Anim. Sci. 12:436-443.

Galvão, A., Valente, L., Skarzynski, D. J., Szóstek, A., Piotrowska-Tomala, K.K., Ramilo, D., Rebordão, M.R., Mateus, L., Ferreira-Dias, G. 2013. Effect of cytokines and ovarian steroids on equine endometrium: an in vitro study. Reprod. Fertil. Dev. 25:985-997.

Galvão, A.M., Ferreira-Dias, G.M., Skarzynski, D.J. 2013. Cytokines and angiogenesis in the corpus luteum. Mediators Inflamm. 2013:420186.

Galvão, A.M., Szóstek, A., Skarzynski, D. J., Ferreira-Dias, G.. 2013. Role of tumor necrosis factor-a, Interferon-g and Fas-ligand regulate nitric oxide activity in the equine corpus luteum. Cytokines 64:18-21.

Mateus, L., Henriques, S., Merino, C., Pomba, C., Lopes da Costa, L., Silva, E. 2013. Virulence genotypes of Escherichia coli canine isolates from pyometra, cystitis and fecal origin. Vet. Microbiol. 166:590–594.

Pimenta, J., Sardinha, J., Marques, C.C., Domingos, A., Baptista, M.C., Barbas, J.P., Martins, I.C., Mesquita, P., Pessa, P., Soares, R., Viegas, A., Cabrita, E., Horta, E.M., Fontes, C.A., Prates, A.M., Pereira, M.L. 2013. Inhibition of ovine in vitro fertilization by anti-Prt antibody: hypothetical model for Prt/ZP interaction. Reprod. Biol. Endocrinol. 11:25.

Pimenta, J., Viegas, A., Sardinha, J., Martins, I.C., Cabrita, E.J., Fontes, C.M.G.A., Prates, J.A., Pereira, R.M.L.N. 2013. NMR solution structure and SRP54M predicted interaction of the N-Terminal sequence (1-30) of the ovine Doppel protein. Peptides 49:32–40.

Prates, E.G., Alves, S., Marques, C.C., Baptista, M.C., Horta, A.E.M., Bessa, R.J.B., Pereira, R.M. 2013. Fatty acid composition of porcine cumulus oocyte complexes (COC) during maturation: effect of the lipid modulators trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) and forskolin. In Vitro Cel. Dev. Biol. Anim. 49:335–345.

Prates, E.G., Marques, C.C., Baptista, M.C., Vasques, M.I., Carolino, N., Horta, A.E.M., Charneca, R., Nunes, J.T., Pereira, R.M. 2013. Fat area and lipid droplets morphology of porcine oocytes during in vitro maturation with trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) and forskolin. Animal 7:602-609.

Romão, R., Marques, C.C., Baptista, M.C., Vasques, M.I., Barbas, J.P., Horta, A.E.M., Carolino, N., Bettencourt, E., Plancha, C., Rodrigues, P., Pereira, R.M. 2013. Evaluation of two methods of vitro production of sheep embryos using fresh or cryopreserved semen. Small Rum. Res. 110:36-41.

Szóstek, A., Lukasik K., Ferreira-Dias, G.M., Skarzynski, D.J. 2013. Impairment of the interleukin system in equine endometrium in the course of endometrosis. Biol. Reprod. 89:79.

Torres, A., Batista, M., Diniz, P., Mateus, L., Lopes-da-Costa, L. 2013. Embryo-luteal cells co-culture: an in vitro model to evaluate steroidogenic and prostanoid bovine early embryo-maternal interactions. In Vitro Cel. Dev. Biol. Anim. 49:134-146.

Torres, A., Chagas e Silva, J., Deloche, M.C., Humblot, P., Horta, A.E., Lopes-da-Costa, L. 2013. Secondary corpora lutea induced by HCG treatment enhanced demi-embryo survival in lactating high-yielding dairy cows. Reprod. Domest. Anim. 48:643-650.

Torres, A., Chagas E Silva, J., Diniz, P., Lopes-da-Costa, L. 2013. Evaluation of treatments with hCG and carprofen at embryo transfer in a demi-embryo and recipient virgin heifer model. Animal 7:1317-1322.

Torres, A., Silva, J.F., Bernardes, N., Sales Luís, J., Lopes da Costa, L. 2013. 64, XX, SRY-negative, testicular DSD syndrome in a Lusitano horse. Reprod. Domest. Anim. 48:e33-37.

 

2012


Alexandre-Pires, G., Mateus, L., Martins, C., Ferreira-Dias, G. 2012. Seasonal changes in testes vascularisation in the domestic cat (Felis domesticus): evaluation of microvasculature, angiogenic activity and endothelial cell expression. Anat. Res. Int. 2012:583798.

Batista, M., Torres, A., Diniz, P., Mateus, L., Lopes-da-Costa, L. 2012. Development of a bovine luteal cell in vitro culture system uitable for co-culture with early embryos. In Vitro Cell. Dev. Biol. Anim. 48: 583-592.

Benedito, R., Woeste, M., Zamnykal, M., Radtke, F., Duarte, A., Rocha, S., Casanovas, O., Pytowski, B., Adams, R. 2012. Notch-dependent VEGFR3 upregulation enables angiogenesis without VEGF/VEGFR2 signalling Nature  484(7392):110-114

Camelo, S., Raoul, W., Lavallete, S., Callipe, B., Cristofaro, B., Levy, O., Houssier, M., Sulpice, E., Jonet, L., Klein, C., Devevre, E., Thuret, G., Duarte, A., Eichmann, C.A., Leconte, L., Guillonneau, X., Sennlaub, F. 2012. Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages. Angiogenesis 15:609-622.

Galvão, A., Henriques, S., Pestka, D., Lukasik, K., Skarzynski, D., Mateus, L.M., Ferreira-Dias, G. 2012. Equine luteal function regulation may depend on the interaction between cytokines and vascular endothelial growth factor: an in vitro studyBiol. Reprod. 86:187.

Galvão, A., Skarzynski, D.J., Szóstek, A., Silva, E., Tramontano, A., Mollo, A., Mateus, L., Ferreira-Dias, G. 2012. Cytokines tumor necrosis factor-a and Interferon-g participate in modulation of the equine corpus luteum as autocrine and paracrine factorsJ. Reprod. Immunol. 93:28–37.

Galvão, A., Rebordão, M.R., Szóstek, A., Skarzynski, D., Ferreira-Dias, G. 2012. Cytokines and neutrophil extracellular traps and in the equine endometrium: friends or foes? Pferdeheilkunde 28: 4-7.

Kowalczyk-Zieba, I., Boruszewska, D., Saulnier-Blache, J.S., Lopes Da Costa, L., Jankowska, K., Skarzynski, D.J., Woclawek-Potocka, I. 2012. Lysophosphatidic acid action in the bovine corpus luteum -an in vitro study. J. Reprod. Dev. 58:661-671.

Laranjeiro, R.,  Alcobia, I., Gomes, A.C., Saavedra, P., Carvalho, C.,  Duarte, A., Cidadão, A., Parreira, L. 2012. The Notch ligand Delta-like 4 regulates multiple stages of early hemato-vascular development. PLoS ONE 7:e34553

Larrivee, B., Prahst, C., Gordon, E., Del Toro, R., Duarte, A., Mathivet, T., Simons, M., Eichmann, A. 2012. Alk1 signaling inhibits angiogenesis by cooperating with the Notch pathway. Dev. Cell  22:489-50

Liu, R., Trindade, A., Sun, Z., Kumar, R., Weaver, F.A., Krasnoperovv, Naga, K., DUARTE A, Gill, P.S. 2012. Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues. Biochem. Biophys. Res. Comm. 418:173-179.  

Pimenta, J., Dias, F., Marques, C., Baptista, M., Vasques, M., Horta, A., Barbas, J., Soares, R., Mesquita, P., Cabrita, E., Fontes, C., Prates, J., Pereira, R. 2012. The Prion-like protein Doppel enhances ovine spermatozoa fertilizing ability. Reprod. Domest. Anim. 47:196-202.  

Pimenta, J., Domingos, A., Santos, P., Marques, C.C., Cantante, C., Santos, A., Barbas, J.P., Baptista, M.C., Horta, A.E.M., Viegas, A., Mesquita, P., Gonçalves, J., Fontes, C., Prates, J.A.M., Pereira, R.M.L.N. 2012. Is prnt a pseudogene? Identification of ram Prt in testis and ejaculated spermatozoa. PLoS ONE 7: e42957. 

Remédio, L., Carvalho, T., Caiado, F., Bastos-Carvalho, A., Martins, D., Duarte, A., Yagita, H., Dias, S. 2012. Context- and cell-dependent effects of Delta-like 4 targeting in the bone marrow microenvironment. PLoS ONE  7:e52450. 

Silva, E., Henriques, S., Brito, S., Ferreira-Dias, G., Lopes-da-Costa, L., Mateus, L. 2012. Canine endometrial changes in toll-like receptors and prostaglandin production throughout the oestrous cycle. J. Reprod. Immunol.  96:45–57.

Szóstek A.Z., Siemieniuch, M.J., Galvão, A.M., Lukasik, K., Zieba, D., Ferreira-Dias, G.M., Skarzynski, D.J. 2012. Effects of cell storage and passage on basal and oxytocin-regulated prostaglandin secretion by equine endometrial epithelial and stromal cells. Theriogenology 77:1698–1708.

SzósteK, A. Z., Siemienuch, M.J., Galvão, A.M., Kukasik, K., Ferreira-Dias, G., Skarzynski, D. J. 2012. mRNA transcription of prostaglandin synthases and their products in the equine endometrium in the course of fibrosis. Theriogenology 78:768–776.

Trindade, A., Djokovic, D., Gigante, J., Badenes, M., Pedrosa, A.R., Fernandes, A.C., Lopes-da-Costa, L., Krasnoperov, V., Liu, R., Gill, P.S., Duarte, A. 2012. Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis. PLoS ONE 7:e29863.

 

2011


Ferreira-Dias, G., Costa, A.S., Korzekwa, A., Mateus, L., Redmer, D., Lukasik, K., Szóstek, A., Woclawek-Potocka,I., Skarzynski, D.J. 2011. Nitric oxide stimulates progesterone and prostaglandin E2 secretion, and angiogenic activity in the equine corpus luteum. Domest. Anim. Endocrinol. 40:1-9.

Lapa, M., Marques, C.C., Alves, S.P., Vasques, M.I., Baptista, M.C., Carvalhais, I., Horta, A.E.M., Bessa, R.J.B., Pereira, R.M. 2011. Effect of trans-10 cis-12 conjugated linoleic acid (t10,c12 CLA) on bovine oocyte competence and fatty acid composition. Reprod. Domest. Anim. 46:904–910.

Lopes-da-Costa, L., Chagas e Silva, J., Deloche, M.C., Jeanguyot, N., Humblot, P., Horta, A.E. 2011. Effects of embryo size at transfer (whole versus demi) and early pregnancy progesterone supplementation on embryo growth and pregnancy-specific protein bovine concentrations in recipient dairy heifers. Theriogenology 76:522-531.

Real, C., Remédio, L., Caiado, F., Igreja, C., Borges, C., Trindade, A., Pinto-do-Ó, P., Yagita, H., Duarte, A., Dias, S. 2011. Bone marrow-derived Endothelial Progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis PLoS ONE 6:e18323

 

2010


Del Toro, R., Prahst, C., Mathivet, T., Siegfried, G., Kaminker, J.S., Larrivee, B., Breany, C., Duarte, A., Takakura, N., Fukamizu, A., Penninger, J., Eichmann, A. 2010. Identification and functional analysis of endothelial tip cell-enriched genes. Blood 116:4025-33.

Djokovic, D., Trindade, A., Gigante, J., Badenes, M., Silva, L., Liu, R., Li, X., Gong, M., Krasnoperov, V. Gill, P.S., Duarte, A. 2010. Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis. BMC Cancer 10:641.

Galvão, A., Ramilo, D., Skarzynski, D.J., Lukasik, K., Tramontano, A., Mollo, A., Mateus, L., Ferreira-Dias, G. 2010. Is Fas/Fas ligand system involved in corpus luteum functional regression? Biol. Reprod. 83:901-908.

Horta, A.E.M., Barbas, J.P., Marques, C.C., Baptista, M.C., Vasques, M.I., Pereira, R.M., Mascarenhas, R.D., Cavaco-Gonçalves, S. 2010. Improvement of fertility in vaginal artificially inseminated ewes after local treatment with misoprostol and terbutaline sulphate. Reprod. Domest. Anim. 45:e412-e416.

Mesquita, P., Batista, M., Marques, M.R., Santos, I.C., Pimenta, J., Silva Pereira, M., Carolino, I., Santos Silva, F., Oliveira Sousa, M.C., Gama, L.T., Fontes, C.M., Horta, A.E., Prates, J.A., Pereira, R.M. 2010. Prion-like Doppel gene polymorphisms and scrapie susceptibility in portuguese sheep breeds. Anim. Genet. 41:311-314.

Silva, E., Leitão, S., Henriques, S., Kowalewski, M. P., Hoffmann, B., Ferreira-Dias, G., Lopes da Costa, L., Mateus, L. 2010. Gene transcription of TLR2, TLR4, LPS ligands and prostaglandin synthesis enzymes are up-regulated in canine uteri with cystic endometrial hyperplasia-pyometra complex. J.  Reprod. Immunol. 84:66–74.

Valente, S., Pereira, R.M., Baptista, M.C., Marques, C.C., Vasques, M.I., Silva Pereira, M.V.C., Horta, A.E.M., Barbas, J.P. 2010. In vitro and in vivo fertility of ram semen cryopreserved in different extenders. Anim. Reprod. Sci.  117:74-77.

 

2009


Silva, E., Leitão, S., Tenreiro, T., Pomba, C., Nunes, T., Lopes da Costa, L., Mateus, L. 2009. Genomic and phenotypic characterization of E. coli isolates recovered from the uterus of puerperal dairy cows. J. Dairy Sci. 92:6000-6010.

Silva, E., Leitão, S., Ferreira-Dias, G., Lopes da Costa, L., Mateus, L. 2009. Prostaglandin synthesis genes are differentially transcripted in normal and pyometra endometria of bitches. Anim. Reprod. Sci.   44:200-203.

Carvalho, M., Mateus, L., Afonso, F., Van Harten, S., Alfaro Cardoso, L., Redmer, D.A., Ferreira-Dias, G. 2009. Testicular angiogenic activity in response to food restriction in rabbit. Anim. Reprod. Sci.   137:509–515.

Pereira, R.M., Mesquita, P., Batista, M., Baptista, M.C., Barbas, J.P., Pimenta, J., Santos, I.C., Marques, M.R., Vasques, M.I., Silva Pereira, M., Santos Silva, F., Oliveira Sousa, M.C., Fontes, C.M., Horta, A.E., Prates, J.A., Marques, C.C. 2009. Doppel gene polymorphisms in Portuguese sheep breeds: Insights on ram fertility. Anim. Reprod. Sci.  114:157-166.

Pereira, R.M., Marques, C.C., Baptista, M.C., Vasques, M.I., Horta A.E.M. 2009. Embryos and culture cells: a model for studying the effect of progesterone. Anim. Reprod. Sci.  111:31-40.

 

BOOK CHAPTERS


Mateus, L., Eilts, B. Cystic endometrial hyperplasia and Pyometra. 2010. In: Textbook of Veterinary Internal Medicine. Ettinger, S.J.; Feldman, E. C. (ed).5th edition. Chapter 302, pp 1959-1967.

Fradinho, M.J., Correia, M.J., Vila-Viçosa, M.J.C., Farrin, A., Harris, P.A., Bessa, R. J.B., Caldeira, R. M., Ferreira-Dias, G. 2009. Non-Invasive bone assessment by quantitative ultrasonography in Lusitano suckling foals: A preliminary study. In: Applied Equine Nutrition and Training. Arno Lindner (ed). Equine Nutrition and Training Conference (ENUTRACO) 2009. Arbeitsgruppe Pferd, Wageningen Academic Publishers, The Netherlands. Pp:191-196.

Fradinho, M. J., Barbosa, M., Vila-Viçosa, M.J.C., Rosa, A., Perestrello, F., Caldeira, R.M., Ferreira-Dias, G. 2010. Effect of growth rate on plasma leptin and bone markers, and metacarpal ultrasound measurements in the young Lusitano horse. In: “The impact of nutrition on the health and welfare of horses”. A. D. Ellis, A. C. Longland, M. Coenen and N. Miraglia (ed.). EAAP publication, nº 128. Pp: 308-313.

Botelho, M., Rebordão, M.R., Galvão, A.M., Pinto Bravo, P., Piotrowska-Tomala, K., Szóstek, A.Z., Wiczkowski, W., Piskula, M., Skarzynski, D.J., Fradinho, M.J., Ferreira-Dias, G.M. 2012. Phytoestrogen coumestrol and its metabolite in mares’ plasma after clover mixed pasture and alfalfa pellets ingestion. In:Forages and grazing in horse nutrition”. M. Saastamoinen, M.J. Fradinho, A.S.Santos and N. Miraglia (ed.). Wageningrn Academic Publishers. EAAP publication nº 132. Pp: 49-53.

Fradinho, M.J., Correia, M.J., Beja, F., Rosa, A., Perestrello, F., Bessa, R.J.B., Ferreira-Dias, G., Caldeira, R.M. 2012. Effects of foaling season on growth and development of Lusitano sucking foals raised on extensive grazing systems. In: Forages and grazing in horse nutrition. M. Saastamoinen, M.J. Fradinho, A.S. Santos and N. Miraglia (ed.). EAAP publication, nº 132. pp: 315-318.

Pimenta, J., Pereira, R.M.L.N. 2013. New perspectives on the study of prion and prion like proteins: key roles in the physiology of sperm and male fertility. In: Spermatozoa Biology, Motility and Function and Chromosomal Abnormalities. Editor: Brenda T. Erickson. Nova Science Publishers, Inc. New York  ISBN: 978-1-63117-020-1

Pimenta, J., Prates, J.A.M., Pereira, R.M.L.N. 2012. Prion gene complex: from prion diseases to male fertility. In: Horizons in Neuroscience Research, Volume 6, Chapter 12. Editors: Andres Costa and Eugenio Villalba. Nova Science Publishers, Inc. New York, pp. 283-304; ISBN: 978-1-62100-080-8 (ebook) and ISSN: 2159-113X.